Integra LifeSciences Satellite: Changing the Paradigm of Soft Tissue Reconstruction: Clinical Outcomes and Value of Integra Dermal Matrices. Sat, Sep 21 9:15-10:00 a.m.

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Various surgical techniques exist for lower extremity (LE) reconstruction but limited high-quality data has been generated to inform treatment strategies. This symposium will focus on the results of 2 long-term, retrospective analyses of patients presenting to the University of Pennsylvania Hospital System over the course of 10 years. One study compared the clinical effectiveness and cost of three common surgical reconstructive modalities for LE defects (Free Flaps, Local Tissue Rearrangement, and Bilayer collagen-GAC wound matrix) using multi-institutional data and rigorous matching. The second study describes a multihospital experience of reconstructive surgeons utilizing Bilayer collagen-GAC wound matrices in lower extremity soft tissue reconstruction with the goals to (1) characterize a suitable patient population, (2) categorize failures to optimize patient selection, and (3) determine wound factors affecting success. Together, these studies demonstrate that lower extremity reconstruction can be effectively performed using multiple modalities with varying degrees of success and costs and suggests a specific patient population for which Bilayer collagen-GAC wound matrix may be successfully utilized in comparison to free flaps and local tissue rearrangement.